BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B cells
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چکیده
منابع مشابه
BAFF augments IgA2 and IL‐10 production by TLR7/8 stimulated total peripheral blood B cells
Class-switching of B cells to IgA can be induced via both T-cell-dependent and T-cell-independent mechanisms. IgA is most predominantly produced mucosally and is important for combating infections and allergies. In contrast to mice, humans have two forms of IgA; IgA1 and IgA2 with diverse tissue distribution. In early life, IgA levels might be sub-optimal especially during the fall season when ...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2017
ISSN: 0014-2980
DOI: 10.1002/eji.201646861